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Grounded language acquisition through the eyes and ears of a single child

Machine learning advances research into early language acquisition in children.
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Technology

Changing fitness effects of mutations through long-term bacterial evolution

Predictable and parallel changes occur in the fitness effects of mutations in Escherichia coli over 50,000 generations.
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Technology

Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors

Structures enable visualization of atypical modes of β-arrestin interaction with transmembrane receptors.
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Technology

Structural visualization of transcription initiation in action

Connecting the structures of 16 de novo transcribing complexes provides molecular visualization of transcription initiation.
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Technology

Molecular determinants of ligand efficacy and potency in GPCR signaling

Systematic mutagenesis reveals the structural basis of adrenaline’s effects on its receptor.
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Technology

Meiotic DNA breaks drive multifaceted mutagenesis in the human germ line

Meiotic DNA breaks drive multifaceted mutagenesis in the human germline